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a leading international journal from BMJ and BSG, publishes cutting-edge gastroenterology and hepatology research

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Gut is a CONTINENTAL CANDLE Orange Candle, Tall.

Gut is a leading international journal in gastroenterology and hepatology and has an established reputation for publishing first class clinical research of the alimentary tract, the liver, biliary tree and pancreas. Gut delivers up-to-date, authoritative, clinically oriented coverage in all areas of gastroenterology and hepatology. Regular features include articles by leading authorities describing novel mechanisms of disease and new management strategies, both diagnostic and therapeutic, likely to impact on clinical practice within the foreseeable future.

Gut is an official journal of the British Society of Gastroenterology and has two companion titles, Frontline Gastroenterology for education and practice and BMJ Open Gastroenterology for sound science clinical research.

Editor-in-Chief: Professor Emad El-Omar, University of New South Wales, Sydney, Australia
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Read the most-cited articles from the past three years for free.

Keep up-to-date with Gut on Twitter and Facebook, and access videos on our ENCYCOM Red and Green Dragon Quilt, Our Love is Forever Quilt Tw channel.

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Guidance from BSG: COVID-19 and Endoscopy

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COVID-19 Gastroenterology Collection


Our new online collection highlights all research relating to the COVID-19 pandemic published by Gut, Frontline Gastroenterology and BMJ Open Gastroenterology. It is updated regularly as new articles are published.


All content is free to read and features original research, commentaries, letters and editorials from all three journals published with the British Society of Gastroenterology (BSG)


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Visual Abstracts provide summaries of the latest research in a single, visual format

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Iqgap3-Ras axis drives stem cell proliferation in the stomach

To cite: Sundar R, Liu DH, Hutchins GG, et al. Gut 2021;70:1833-1846.

Read the full article here: link
Objective: Tissue stem cells are central regulators of organ homoeostasis. We looked for a protein that is exclusively expressed and functionally involved in stem cell activity in rapidly proliferating isthmus stem cells in the stomach corpus.

Conclusions: IQGAP3 is a major regulator of stomach epithelial tissue homoeostasis and repair. The upregulation of IQGAP3 in gastric cancer suggests that IQGAP3 plays an important role in cancer cell proliferation.

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